Peptic ulcer disease: changes it has undergone over the past 50 years

Peptic ulcer complications requiring surgery: what has changed in the last 50 years in Turkey.

BACKGROUND/AIMS The incidence and prevalence of peptic ulcer disease has decreased in recent years, but it is not so easy to make the same conclusion when complications of peptic ulcer are taken into consideration. The aim of this study is to determine the time trends in complicated peptic ulcer disease and to state the effects of H2 receptor blockers, proton pump inhibitors (PPI), and H. pylor...

Omeprazole: is it the answer of peptic ulcer disease?

Omeprazole, the acid pump inhibitor, is a new approach to the regulation of gastric acidity. Its discovery has led to new insights into the mechanism of gastric secretion, pathogenesis of certain gastrointestinal tumours and the development of new treatments for peptic ulcer. Recently this product has been marketed in Pakistan with promising results, but is yet to be evaluated in terms of long ...

Peptic Ulcer Disease: Introduction

Peptic ulcer disease represents a serious medical problem. Approximately 500,000 new cases are reported each year, with 5 million people affected in the United States alone. Interestingly, those at the highest risk of contracting peptic ulcer disease are those generations born around the middle of the 20th century. Ulcer disease has become a disease predominantly affecting the older population,...

Peptic Ulcer Disease

Peptic ulcer disease prevalence is decreasing in the West, except in certain populations such as immigrants. [2] A UK population-based cohort study reported an overall incidence of uncomplicated peptic ulcer as being 0.75 cases per 1,000 person-years, declining from 1.1 to 0.52 cases per 1,000 person-years between 1997 and 2005. A reduction in H. pylori-related peptic ulcers, changing patterns ...

Peptic Ulcer Disease